Innovative Methodology Recovery of Slow Potentials in AC-Coupled Electrocorticography: Application to Spreading Depolarizations in Rat and Human Cerebral Cortex
نویسندگان
چکیده
Jed A. Hartings,* Tomas Watanabe,* Jens P. Dreier, Sebastian Major, Leif Vendelbo, and Martin Fabricius Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research; Undersea Medicine Department, Naval Medical Research Center, Silver Spring, Maryland; Center for Stroke Research, Charité Universitätsmedizin Berlin, Berlin, Germany; and Department of Clinical Neurophysiology, Glostrup Hospital, Copenhagen, Denmark
منابع مشابه
Recovery of slow potentials in AC-coupled electrocorticography: application to spreading depolarizations in rat and human cerebral cortex.
Cortical spreading depolarizations (spreading depressions and peri-infarct depolarizations) are a pathology intrinsic to acute brain injury, generating large negative extracellular slow potential changes (SPCs) that, lasting on the order of minutes, are studied with DC-coupled recordings in animals. The spreading SPCs of depolarization waves are observed in human cortex with AC-coupled electroc...
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39 Cortical spreading depolarizations (spreading depressions and peri-infarct 40 depolarizations) are a pathology intrinsic to acute brain injury, generating large negative 41 extracellular slow potential changes (SPCs) which, lasting on the order of minutes, are 42 studied with DC-coupled recordings in animals. The spreading SPCs of depolarization 43 waves are observed in human cortex with AC-...
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Background and Purpose—Spreading depolarizations, characterized by large propagating, slow potential changes, have been demonstrated with electrocorticography in patients with cerebral hemorrhage and ischemic stroke. Whereas spreading depolarizations are harmless under normal conditions in animals, they cause or augment damage in the ischemic brain. A fraction of spreading depolarizations is ab...
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BACKGROUND AND PURPOSE Spreading depolarizations, characterized by large propagating, slow potential changes, have been demonstrated with electrocorticography in patients with cerebral hemorrhage and ischemic stroke. Whereas spreading depolarizations are harmless under normal conditions in animals, they cause or augment damage in the ischemic brain. A fraction of spreading depolarizations is ab...
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